Abstract:    To assess the effectiveness of Stress Soothing Sustenance Education on knowledge and attitude on stress eating among night shift working nurses at selected hospitals in Dindigal district. Methodology: Quantitative approach, A quasi experimental design was adopted to assess the effectiveness of stress soothing sustenance education on knowledge and stress eating attitude among night working nurses (100 samples in selected hospitals in Dindigal district. Purposive sampling technique was utilized to choose the samples. Stress Soothing Sustenance Education was administered, and the level of knowledge and stress eating attitude was assessed by using a self structured questionnaire and modified Salzburg stress eating attitude scale and contrasted with the pre test and post test levels of knowledge and stress eating attitude among night working nurses. Results: The Research findings revealed that the post test mean knowledge score of night shift nurses was 7.59 and the post test mean stress eating attitude score was 31.22. The calculated paired ‘t’ value (55.458 and 22.819) for knowledge and stress eating attitude shows that there was a high statistical differences at p < 0.001.Conclusion: The results revealed that the stress soothing sustenance education was an effective intervention tool in enhancing the knowledge and stress eating attitude regarding stress reducing dietary practices among night shift nurses.