INTERNATIONAL JOURNAL FOR INNOVATIVE RESEARCH IN MULTIDISCIPLINARY FIELD

Abstract:  Background: Allergic rhinitis or hay fever is a common allergic condition that primarily affects the nose and nasal passages, characterized by inflammation of the nasal mucosa. It occurs when the immune system reacts to allergens in the environment, such as pollen, dust mites, pet dander, or mold spores, leading to a range of symptoms. Objective: This study evaluates the therapeutic impact of individualized Homoeopathic treatment on the clinical symptom score and the reduction of systemic inflammatory biomarkers in patients with chronic allergic rhinitis. Methods: This single-case observational study, conducted at the Materia Medica Department's outpatient clinic, evaluated the clinical impact of individualized Nux vomica supplemented by integrated supportive therapies over five months. Patient progress was monitored using the Total Nasal Symptom Score (TNSS) to quantify symptomatic relief, while the physiological and immunomodulatory effects were assessed through the longitudinal tracking of systemic biomarkers, specifically serum Immunoglobulin E (IgE) and Absolute Eosinophil Count (AEC). Results: Following the intervention, a rapid reduction in the clinical symptom burden was evidenced by improved Total Nasal Symptom Scores (TNSS) within the first six days. Long-term longitudinal analysis further demonstrated a substantial down-regulation of both serum IgE and AEC, with these physiological changes directly correlating to a marked decrease in the frequency of symptomatic recurrence. Conclusion: While constitutional prescribing often necessitates a more extended induction phase compared to the rapid action of acute remedies, it appears to exert a more substantive influence on the fundamental disease process. The significant reductions observed in both immunological biomarkers and symptomatic recurrence suggest a deep-seated therapeutic effect; however, the inherent constraints of a single-case design necessitate caution, as they preclude the definitive establishment of a direct causal relationship.