Antidiabetic activity of endophytic fungi isolated from Aegle marmelos and Momordica charantia
Author(s): Athharv Nalavday
Authors Affiliations:
Institute of Biosciences and Technology, MGM University, Chh. Sambhajinagar, Maharashtra, India
DOIs:10.2015/IJIRMF/202501012     |     Paper ID: IJIRMF202501012Alloxan-induced oxidative stress has been demonstrated to harm beta-cells in the pancreas and result in hyperglycemia. In Ayurveda, Aegle marmelos leaf extract is used as a diabetes medication. The current study looked at ability of Aegle marmelos to prevent experimental diabetes and its antioxidant capacity. In those with alloxan diabetes, a methanolic extract of Aegle marmelos was proven to lower blood sugar levels. As advised by Indian Ayurveda, bilva has been widely used to treat diabetes and intestinal disorders. It is also frequently used to treat diabetes and other metabolic disorders. Karela, balsam pear, bitter melon, and bitter gourd. Indigenous communities in Asia, South America, India, and East Africa frequently employ Momordica charantia to treat diabetes and other metabolic disorders because of its ability to lower blood sugar levels. Through a variety of hypothesised processes, Momordica charantia has been shown to have positive effects in numerous pre-clinical trials. It was out that the endophytic fungi that were separated from the fruit and leaf samples were not the same. Each fungal species had a different morphological description. Based on their appearance, we discovered that the samples were surrounded by Aspergillus versicolor, Aspergillus niger, Penicillium verhagenii, and Fusarium oxysporum fungi. Each fungal species exhibited different levels of inhibitory properties towards the α-amylase, ranging from 53% to 30%, 36% to 19%.
Athharv Nalavday (2025); “Antidiabetic activity of endophytic fungi isolated from Aegle marmelos and Momordica charantia”, International Journal for Innovative Research in Multidisciplinary Field, ISSN(O): 2455-0620, Vol-11, Issue-1, Pp.82-89. Available on – https://www.ijirmf.com/ DOIs:10.2015/IJIRMF/202501012
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