30, January 2026

Cytotoxic Effect of Pantoprazole on Onion (Allium cepa) Root Tip cells

VOLUME-12; ISSUE-1; JAN-2026

Author(s): Srishti Shivalika, Dharmshila Kumari

Authors Affiliations:

1Research Scholar, 2 Professor

1,2University Department of Zoology, T.M.B.U. Bhagalpur, Bihar, India

DOIs:10.2015/IJIRMF/202601018     |     Paper ID: IJIRMF202601018


Abstract
Keywords
Cite this Article/Paper as
References

Abstract: The increasing use of pharmaceuticals like Pantoprazole, a proton pump inhibitor (PPI), has raised environmental concerns due to their persistence and potential cytotoxic. This study investigates the cytotoxic effects of Pantoprazole on the root meristem cells of Allium cepa (onion), a well-established plant bioindicator. The root tips were exposed to various concentrations of Pantoprazole (10 and 20 mg/l) for 72 hours. The mitotic index (MI) and root growth inhibition were evaluated. The results indicated a significant dose-dependent decline in MI. These findings suggest that Pantoprazole, when present in the environment, can induce genetic damage in plant systems and may potentially affect broader ecological processes.

   
Keywords: Pantoprazole, Allium cepa, genotoxicity, chromosomal aberrations, mitotic index.

Srishti Shivalika, Dharmshila Kumari (2026); Cytotoxic Effect of Pantoprazole on Onion (Allium cepa) Root Tip cells, International Journal for Innovative Research in Multidisciplinary Field, ISSN(O): 2455-0620, Vol-12, Issue-1, Pp.106-108.          Available on –   https://www.ijirmf.com/

Post Views: 85

Download Full Paper

Download PDF No. of Downloads:12 | No. of Views: 83